Journal of Indian Association of Pediatric Surgeons
Journal of Indian Association of Pediatric Surgeons
                                                   Official journal of the Indian Association of Pediatric Surgeons                           
Year : 2004  |  Volume : 9  |  Issue : 1  |  Page : 20--24

Role of human chorionic gonadotropin (HCG) hormone is undescended testis; a prospective study in 100 children


BA Cheechak, MY Wani, A Hussain, G Hassan 
 Dept. of Surgery, Gandhi Medical College Srinagar, Jammu and Kashmir, India

Correspondence Address:
BA Cheechak
Dept. of Surgery, Gandhi Medical College Srinagar, Jammu and Kashmir
India

ABSTRACT: This is a prospective study of 100 children (122 testes) of Cryptorchidism in whom the role of HCG in causing descent of Cryptorchid testis, making impalpable testis to become palpable and making orchidopexy easier and thus improving surgical outcome, has been evaluated. Among the 70 children (86 testes) treated with HCG, 32 were bilateral, 54 were unilateral; 38 testes were impalpable and 48 testes were palpable. The dose of HCG was 5000 IU in the age group of 1-6 years and 10,000 IU in the age group of 7-12 years given in weekly divided intramuscular injections. Patients were evaluated clinically for, descent, palpability and any complication. Among those patients who did not respond to HCG therapy, 30 patients were operated upon and the surgical outcome was compared with 30 patients who were operated without receiving HCG. In our study, descent occurred more in bilateral (50 percent) testis, as compared to unilateral (32 percent) UDT. The overall success rate was 38.3 percent. HCG was more effective in the age group 4-6 years (63 percent in B/L & 33 percent in U/L) than in 7-9 years (50 percent B/L & 35 percent U/L). We found that 47.3 percent impalpable UDT became palpable after HCG treatment. The best response was seen in palpable testis located prescrotally (72.7 percent) and in low canalicular testes (50 percent). Only 15.78 percent impalpable testis descended after HCG. At 4 months follow up, the success rate dropped to 30.2 percent as there was relapse in 7 testes. We found a statistically significant difference (P0.001) between surgical outcome in patients operated after receiving HCG and those operated without receiving HCG.


How to cite this article:
Cheechak B, Wani M, Hussain A, Hassan G. Role of human chorionic gonadotropin (HCG) hormone is undescended testis; a prospective study in 100 children.J Indian Assoc Pediatr Surg 2004;9:20-24


How to cite this URL:
Cheechak B, Wani M, Hussain A, Hassan G. Role of human chorionic gonadotropin (HCG) hormone is undescended testis; a prospective study in 100 children. J Indian Assoc Pediatr Surg [serial online] 2004 [cited 2021 Apr 22 ];9:20-24
Available from: https://www.jiaps.com/article.asp?issn=0971-9261;year=2004;volume=9;issue=1;spage=20;epage=24;aulast=Cheechak;type=0