|Year : 2020 | Volume
| Issue : 3 | Page : 187
Congenital cervical mass in a neonate with secondary scalp swelling
Arti Khatri1, Nidhi Mahajan1, Chabbi Ranu Gupta2, Ekta Narang3
1 Department of Pathology, Chacha Nehru Bal Chikitsalaya, Geeta Colony, Delhi, India
2 Department of Pediatric Surgery, Chacha Nehru Bal Chikitsalaya, Geeta Colony, Delhi, India
3 Department of Otolaryngology, Chacha Nehru Bal Chikitsalaya, Geeta Colony, Delhi, India
|Date of Submission||18-Oct-2019|
|Date of Decision||14-Dec-2019|
|Date of Acceptance||11-Jan-2020|
|Date of Web Publication||11-Apr-2020|
Dr. Nidhi Mahajan
Room No. 404, 4th Floor, Chacha Nehru Bal Chikitsalaya, Geeta Colony, Delhi - 110 031
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Khatri A, Mahajan N, Gupta CR, Narang E. Congenital cervical mass in a neonate with secondary scalp swelling. J Indian Assoc Pediatr Surg 2020;25:187
|How to cite this URL:|
Khatri A, Mahajan N, Gupta CR, Narang E. Congenital cervical mass in a neonate with secondary scalp swelling. J Indian Assoc Pediatr Surg [serial online] 2020 [cited 2022 Jan 20];25:187. Available from: https://www.jiaps.com/text.asp?2020/25/3/187/282149
A rare entity, congenital cervical neuroblastoma (NB) in a 3–week-old male neonate presenting as a large neck mass is discussed [Figure 1]a and [Figure 1]b. Contrast-enhanced computed tomography [Figure 1]c, fine-needle aspiration cytology, and tissue biopsy lead to a definitive diagnosis [Figure 2]. The patient received two cycles of chemotherapy (adriamycin and cyclophosphamide), however succumbed to death due to sepsis. Congenital NB has a good prognosis and may show spontaneous regression despite metastasis., The indexed case is unique in highlighting the rare site, metastasis at presentation, and associated poor outcome. Prenatal diagnosis of these entities ensures timely management and improved survival.
|Figure 1: (a) Clinical picture of a huge left cervical mass, (b) scalp swelling, (c) contrast.enhanced computed tomography shows a large heterogeneous mass with central necrosis|
Click here to view
|Figure 2: (a) Fine-needle aspiration cytology smears are cellular with sheets of large, round cells with focal rosette formation (Giemsa, ×40), (b) focal presence of neuropil amidst the large cells (Giemsa, ×400), (c) tumor cells show strong immunopositivity for synaptophysin (immunocytochemistry, 3,3'-diaminobenzidine as chromogen, ×100), (d) biopsy shows features of differentiating neuroblastoma (H and E, ×400)|
Click here to view
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
Lonergan GJ, Schwab CM, Suarez ES, Carlson CL. Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: Radiologic-pathologic correlation. Radiographics 2002;22:911-34.
Gorincour G, Dugougeat-Pilleul F, Bouvier R, Lorthois-Ninou S, Devonec S, Gaucherand P, et al
. Prenatal presentation of cervical congenital neuroblastoma. Prenat Diagn 2003;23:690-3.
[Figure 1], [Figure 2]