Home | About Us | Current Issue | Ahead of print | Archives | Search | Instructions | Subscription | Feedback | Editorial Board | e-Alerts | Login 
Journal of Indian Association of Pediatric Surgeons
     Journal of Indian Association of Pediatric Surgeons
Official journal of the Indian Association of Pediatric Surgeons         
 Users Online:669 
  Print this page Email this page   Small font sizeDefault font sizeIncrease font size

Table of Contents   
Year : 2019  |  Volume : 24  |  Issue : 4  |  Page : 310-311

Ileoileocolic intussusception secondary to isolated ectopic pancreatic tissue: An uncommon case

1 Department of Surgical Gastroenterology, Nishtha Surgical Hospital and Research Centre, Patan, Gujarat, India
2 Department of Surgery, SSR Medical College, Belle Rive, Mauritius
3 Department of Surgical Gastroenterology, Samved Hospital, Patan, Gujarat, India
4 Department of Histopathology, Supratech Micropath Laboratory, Ahmedabad, Gujarat, India

Date of Web Publication29-Aug-2019

Correspondence Address:
Dr. Vipul D Yagnik
77, Siddhraj Nagar, Rajmahal Road, Patan - 384 265, Gujarat
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jiaps.JIAPS_245_18

Rights and Permissions


How to cite this article:
Yagnik VD, Dawka S, Prajapati S, Mehta B. Ileoileocolic intussusception secondary to isolated ectopic pancreatic tissue: An uncommon case. J Indian Assoc Pediatr Surg 2019;24:310-1

How to cite this URL:
Yagnik VD, Dawka S, Prajapati S, Mehta B. Ileoileocolic intussusception secondary to isolated ectopic pancreatic tissue: An uncommon case. J Indian Assoc Pediatr Surg [serial online] 2019 [cited 2021 May 13];24:310-1. Available from: https://www.jiaps.com/text.asp?2019/24/4/310/265706


A 10-year-old boy was admitted with chief complaints of abdominal pain, nausea, and vomiting for 3 days. He had not passed stool for 2 days. He had no significant past and personal history. Physical examination showed minimal abdominal distension with a palpable lump in the right lower quadrant. Ultrasonography of the abdomen revealed “bowel within bowel” appearance extending from the umbilical region and the right iliac fossa to the right upper abdomen; the length of the involved segment was 12 cm suggestive of ileocolic intussusception with an echogenic nodule as the lead point [Figure 1]. Laboratory investigations showed a low hemoglobin 9.0 g/dL, increased total leukocyte count (18,000/mm3), and high C-reactive protein level. Other blood investigations were within the standard limit. The patient was sent to the operating room after obtaining written informed consent. At exploration of the abdomen, an ileoileocolic intussusception extending up to the hepatic flexure was found and reduced manually. A small well-circumscribed nodule was observed as a lead point at 50 cm from the ileocecal valve [Figure 2]. We performed wedge resection and single layer closure with polyglactin 910, 3–0 suture. The resected specimen was sent for histopathological examination, which showed submucosal ectopic pancreatic tissue with Heinrich type 1 elements [Figure 3]. The postoperative course was unremarkable.
Figure 1: Bowel within bowel appearance with focal echogenic lead point within suggestive of intussusception secondary to the pathological lead point

Click here to view
Figure 2: A well-circumscribed nodule in the ileum

Click here to view
Figure 3: Ileal mucosa with submucosal ectopic pancreatic tissue composed of duct, acini, and islet cells (left, H and E stain, ×4; and right, H and E stain, ×40)

Click here to view

Ectopic pancreatic tissue or heterotopic pancreatic tissue is defined as pancreatic tissue lacking anatomical and vascular continuity with the pancreas and found anywhere within the abdomen.[1] Postmortem studies have demonstrated ectopic pancreatic tissue in approximately 0.55%–13.7% of autopsies.[2] Jean Schultz presented the first reported case of ectopic pancreatic tissue within a diverticulum in 1727.[2] It is most commonly found in the stomach, duodenum, and jejunum. The symptoms are related to size and mucosal relation.[2] Classic dictum teaches that the frequency of pathological lead point (PLP) in pediatric intussusception increases with age. However, Lin et al. found that those >2 years old, especially between 2 and 5 years of age (47.7%), were more likely to have PLPs than those >5 years old (30.8%).[3] Although the PLP is conventionally believed to be more common in older children as compared to younger, 97.4% of ileocolic intussusception cases were idiopathic regardless of the age.[4] On extensive literature search, we found 21 cases reported so far.[5] In a review of 21 cases with intussusception due to ectopic pancreatic tissue, 15 patients were <2 years of age. Only three cases over 4 years of age have been reported in the pediatric age group.[6] Ileoileocolic intussusception in pediatric patients over 4 years of age has not been reported to date. It is essential to look for the PLP, and palpation is required mainly for a submucosal location that may not be obvious on inspection. Resection is considered the treatment of choice to prevent recurrence. Von Heinrich has classified ectopic pancreas into three types. Type 1 ectopic pancreatic tissue is structured with ducts, acini, and islets. Type II ectopic pancreas shows ducts and acini while Type III consists of ducts only.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form, the legal guardian has given his consent for images and other clinical information to be reported in the journal. The guardian understands that his name and initials will not be published and due efforts will be made to conceal identity, but anonymity cannot be guaranteed.

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.

   References Top

Lai EC, Tompkins RK. Heterotopic pancreas. Review of a 26 year experience. Am J Surg 1986;151:697-700.  Back to cited text no. 1
Dolan RV, ReMine WH, Dockerty MB. The fate of heterotopic pancreatic tissue. A study of 212 cases. Arch Surg 1974;109:762-5.  Back to cited text no. 2
Lin XK, Xia QZ, Huang XZ, Han YJ, He GR, Zheng N, et al. Clinical characteristics of intussusception secondary to pathologic lead points in children: A single-center experience with 65 cases. Pediatr Surg Int 2017;33:793-7.  Back to cited text no. 3
Rubinstein JC, Liu L, Caty MG, Christison-Lagay ER. Pathologic leadpoint is uncommon in ileo-colic intussusception regardless of age. J Pediatr Surg 2015;50:1665-7.  Back to cited text no. 4
Shin HO, Lee SW, Koo H, Hwang JY. Isolated heterotopic pancreas in ileoileal intussusception. J Ultrasound Med 2009;28:545-8.  Back to cited text no. 5
Sundaram J, Menon P, Kumar V, Rao KL, Vaiphei K, Kakkar N, et al. Isolated ileal pancreatic heterotopia causing intussusception with gangrene. Fetal Pediatr Pathol 2015;34:252-6.  Back to cited text no. 6


  [Figure 1], [Figure 2], [Figure 3]


Print this article  Email this article


    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Article in PDF (1,242 KB)
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
* Registration required (free)  

    Article Figures

 Article Access Statistics
    PDF Downloaded73    
    Comments [Add]    

Recommend this journal

Contact us | Sitemap | Advertise | What's New | Copyright and Disclaimer 

  2005 - Journal of Indian Association of Pediatric Surgeons | Published by Wolters Kluwer - Medknow 

Online since 1st May '05