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Journal of Indian Association of Pediatric Surgeons
     Journal of Indian Association of Pediatric Surgeons
Official journal of the Indian Association of Pediatric Surgeons         
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Year : 2011  |  Volume : 16  |  Issue : 1  |  Page : 2-7

Pediatric liver transplantation: A report from a pediatric surgical unit

1 Department of Pediatric Surgery, Narayana Hrudayalaya Hospitals, Bangalore, India
2 Department of Pediatrics and Intensive Care, Narayana Hrudayalaya Hospitals, Bangalore, India
3 Department of Gastroenterology, Narayana Hrudayalaya Hospitals, Bangalore, India
4 Pediatric Solid Organ Transplantation, Alfred Dupont Children's Hospital, Delaware, USA

Correspondence Address:
Sanjay Rao
Department of Pediatric Surgery, Narayana Hrudayalaya Hospitals, 258/A, Bommasandra Industrial Area, Anekal Taluk, Bangalore - 560 099
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-9261.74512

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Background: Liver transplantation is well established worldwide as an effective treatment for end-stage liver disease in children. Acceptance in India has been slow because of considerations of cost, infections, inability to support long-term care, and non-availability of expertise. Aim: This study was designed to report our experience with pediatric liver transplantation. Materials and Methods: Twenty-eight children underwent liver transplantation. Results: Biliary atresia was the commonest indication (n = 15) followed by metabolic liver disease. Twenty-six children had living donor transplants, mothers being the donors in a majority of these. Common surgical complications included bile leaks (n = 3) and vascular problems (n = 6). Common medical complications included infections, acute rejection, and renal failure. Overall, patient survival was 71%, while that for the last 14 cases was 92%. All survivors are doing well, have caught up with physical and developmental milestones and are engaged in age appropriate activities. Conclusions: The study demonstrates the feasibility of a successful pediatric liver transplant program in our country.


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  2005 - Journal of Indian Association of Pediatric Surgeons | Published by Wolters Kluwer - Medknow 

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