Home | About Us | Current Issue | Ahead of print | Archives | Search | Instructions | Subscription | Feedback | Editorial Board | e-Alerts | Login 
Journal of Indian Association of Pediatric Surgeons
     Journal of Indian Association of Pediatric Surgeons
Official journal of the Indian Association of Pediatric Surgeons         
 Users Online:38 
  Print this page Email this page   Small font sizeDefault font sizeIncrease font size
 
Year : 2003  |  Volume : 8  |  Issue : 4  |  Page : 195-201

Optometry of nerve trunks in Hirschsprung's disease.


4, Gorky Terrace, Kolkata 700017

Correspondence Address:
R Bandyopadhyay
4, Gorky Terrace, Kolkata 700017

Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

ABSTRACT: It is well accepted that increased nerve trunk density and thickness are common in aganglionic segments of colon in Hirschsprung's disease (HD). Attempts have been made previously to quantitate the degree of increase in density as well as thickness of nerves. In this study, 36 cases of defective intestinal innervation were analysed, 30 of which were HD. Sections of ganglionic and aganglionic colon were taken and a detailed histological analysis was performed. Nerve trunk were studied in terms of density and thickness. It was found that nerve trunks were more numerous in the aganglionic portion and also thicker compared to those in the ganglionic colon. Average number of nerve trunks in ganglionic and aganglionic colon were 27.50/10 mm2 and 70.28/10 mm2 respectively. Nerve trunks thicker than 45mu was found helpful in the diagnosis of HD when used as additional positive objective criteria apart from absence of ganglion cells. Histopathological study of suspected cases of HD is important as it serves to distinguish cases of HD from those of neuronal intestinal dysplasia (NID) thus helping in selecting the therapeutic approach.






[PDF]*


        
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1275    
    Printed73    
    Emailed0    
    PDF Downloaded142    
    Comments [Add]    

Recommend this journal

 


Contact us | Sitemap | Advertise | What's New | Copyright and Disclaimer 

  2005 - Journal of Indian Association of Pediatric Surgeons | Published by Wolters Kluwer - Medknow 

Online since 1st May '05