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Journal of Indian Association of Pediatric Surgeons
     Journal of Indian Association of Pediatric Surgeons
Official journal of the Indian Association of Pediatric Surgeons         
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Year : 2000  |  Volume : 5  |  Issue : 3  |  Page : 122-127

Melanotic neuroectodermal tumor of infancy : a study of 5 cases.

35C, R.M. Datta Garden Lane , Calcutta-700010

Correspondence Address:
S Das
35C, R.M. Datta Garden Lane , Calcutta-700010

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ABSTRACT: Melanotic Neuroectodermal Tumor (MNET) is an interesting neoplasm seen in children under 1 year of age. The clinical behavior of the tumor is quite different from that of other tumors of neuroectodermal origin. All the 5 cases of MNET that are reported in this study were under the age of 14 months. Four were males and 1 female. In 3 cases the tumor was located in the anterior maxilla, in 1 it was in the mandible, and in another in the skull. A local excision of the tumor with curettage of the bony wall was undertaken in 4 cases and hemimandibulectomy was done in 1. Four of them remined well, but in one case, the tumor recurred within 6 weeks of primary resection. The recurrent tumor was re-excsised and chemotherapy with Endoxan and Doxorubicin was administered. The histopathological picture of the recurrent tumor did not show any difference from the other 4 tumors, except that it was highly cellular with scanty stromal tissues. A review of the literature reveals that though the tumor is generally considered benign, malignancy can occur in 1.9 percent cases and in tumors of head and neck region, the incidence of malignancy is 2.3 percent.

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  2005 - Journal of Indian Association of Pediatric Surgeons | Published by Wolters Kluwer - Medknow 

Online since 1st May '05