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| Year : 1997 | Volume
: 2
| Issue : 4 | Page : 122-125 |
Preliminary study of antibacterial effect of Ozone on pseudomonas Species.
CS Gopal, BB Gupta, MR Sen, AN Gangopadhyay, DK Gupta, PF Mohanty
Division of Pediatric Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005
Correspondence Address:
CS Gopal
Division of Pediatric Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005
 Source of Support: None, Conflict of Interest: None  | Check |
ABSTRACT: Pseudomonas is one of the most common organisms infecting chronic superficial wounds particularly burns and is known to be most difficult to treat. The pre-eminent role of Pseudomonas aeruginosa in hospital infection is due to its resistance to common antiseptics and disinfectants and its ability, to establish itself widely in hospitals. It possesses a considerable degree of natural resistance to many antibiotics. Ozone, the triatomic form of oxygen has powerful oxidizing properties and is known to possess strong antibacterial property, hence has a potential for its use as an antimicrobial agent. A device has (Fig 1) been developed indigenously and jointly by professor S C Gopal and Dr D Pal to deliver ozone made from air instantaneously. The superficial wounds infected with Pseudomonas aeruginosa were exposed to ozone treatment. Its efficacy in controlling infection was judged both in vitro and in vivo by noting the growth of organisms on culture plate and the appearance of healthy granulation tissue respectively. It was found that it is highly effective in controlling wounds infected with Pseudomonas aeruginosa. It is also effective against those wounds infected with Pseudomonas aeruginosa strains, resistant to gentamicin/amikacin. This newer modality of treatment by ozone exposure for superficial wounds infected with Pseudomonas aeruginosa is quite simple and effective and is an effective alternative to treat the wounds where gentamicin/amikacin is ineffective.
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