Journal of Indian Association of Pediatric Surgeons
Journal of Indian Association of Pediatric Surgeons
                                                   Official journal of the Indian Association of Pediatric Surgeons                           
Year : 2011  |  Volume : 16  |  Issue : 1  |  Page : 2--7

Pediatric liver transplantation: A report from a pediatric surgical unit


Sanjay Rao1, Ashley L. J. D'Cruz1, Rajiv Aggarwal2, Supraja Chandrashekar2, G Chetan2, Gayathri Gopalakrishnan3, Stephen Dunn4 
1 Department of Pediatric Surgery, Narayana Hrudayalaya Hospitals, Bangalore, India
2 Department of Pediatrics and Intensive Care, Narayana Hrudayalaya Hospitals, Bangalore, India
3 Department of Gastroenterology, Narayana Hrudayalaya Hospitals, Bangalore, India
4 Pediatric Solid Organ Transplantation, Alfred Dupont Children's Hospital, Delaware, USA

Correspondence Address:
Sanjay Rao
Department of Pediatric Surgery, Narayana Hrudayalaya Hospitals, 258/A, Bommasandra Industrial Area, Anekal Taluk, Bangalore - 560 099
India

Background: Liver transplantation is well established worldwide as an effective treatment for end-stage liver disease in children. Acceptance in India has been slow because of considerations of cost, infections, inability to support long-term care, and non-availability of expertise. Aim: This study was designed to report our experience with pediatric liver transplantation. Materials and Methods: Twenty-eight children underwent liver transplantation. Results: Biliary atresia was the commonest indication (n = 15) followed by metabolic liver disease. Twenty-six children had living donor transplants, mothers being the donors in a majority of these. Common surgical complications included bile leaks (n = 3) and vascular problems (n = 6). Common medical complications included infections, acute rejection, and renal failure. Overall, patient survival was 71%, while that for the last 14 cases was 92%. All survivors are doing well, have caught up with physical and developmental milestones and are engaged in age appropriate activities. Conclusions: The study demonstrates the feasibility of a successful pediatric liver transplant program in our country.


How to cite this article:
Rao S, D'Cruz AL, Aggarwal R, Chandrashekar S, Chetan G, Gopalakrishnan G, Dunn S. Pediatric liver transplantation: A report from a pediatric surgical unit.J Indian Assoc Pediatr Surg 2011;16:2-7


How to cite this URL:
Rao S, D'Cruz AL, Aggarwal R, Chandrashekar S, Chetan G, Gopalakrishnan G, Dunn S. Pediatric liver transplantation: A report from a pediatric surgical unit. J Indian Assoc Pediatr Surg [serial online] 2011 [cited 2020 Feb 27 ];16:2-7
Available from: http://www.jiaps.com/article.asp?issn=0971-9261;year=2011;volume=16;issue=1;spage=2;epage=7;aulast=Rao;type=0