Journal of Indian Association of Pediatric Surgeons
Journal of Indian Association of Pediatric Surgeons
                                                   Official journal of the Indian Association of Pediatric Surgeons                           
Year : 2006  |  Volume : 11  |  Issue : 4  |  Page : 234--238

Value of lung biopsy in pulmonary diseases in children


S Al-Nassar, P Kadamba, Z Habib 
 King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Correspondence Address:
S Al-Nassar
Section of Pediatric Surgery, Department of Surgery (MBC-40), King Faisal Specialist Hospital and Research Centre, P.O. Box 3354, Riyadh 11211
Saudi Arabia

Purpose: Open lung biopsy (OLB) is claimed to be a sensitive tool for the diagnosis of interstitial lung disease. It is reported to be associated with significant morbidity and mortality. Aim: Evaluate whether lung biopsy helped us to make a specific diagnosis, it had resulted in change in therapy and assessment of its morbidity and mortality. Materials and Methods: This was a retrospective analysis of 91 lung biopsies performed in 83 patients between January 2000 and December 2003. These children were allocated to three groups: a. Primary pulmonary pathology (22), b. Immunocompromised (49) i. Primary immunodeficiency (10), ii. Postchemotherapy and BMT (39), c. Pulmonary metastases from solid tumors (20) Results: A specific diagnosis was reached in 87/91 children (95%), but this resulted in a change in therapy (excluding lung meet) in only 23/71 (32%). It is lower in those postchemo/BMT 8/39 (20.6%). Postoperative morbidity occurred in 11/91 (12%) but procedure-related morbidity was only (3.2%). Death within a month of the biopsy occurred in six children (6.5%), with one (1.1%) procedure-related. Conclusion: 1. OLB is a safe procedure at our institution. 2. OLB is a sensitive tool to determine the specific cause of pulmonary infiltrate. 3. Change in therapy expected to be only in 32% of patients and even lower in postchemotherapy and BMT children.


How to cite this article:
Al-Nassar S, Kadamba P, Habib Z. Value of lung biopsy in pulmonary diseases in children.J Indian Assoc Pediatr Surg 2006;11:234-238


How to cite this URL:
Al-Nassar S, Kadamba P, Habib Z. Value of lung biopsy in pulmonary diseases in children. J Indian Assoc Pediatr Surg [serial online] 2006 [cited 2020 Apr 4 ];11:234-238
Available from: http://www.jiaps.com/article.asp?issn=0971-9261;year=2006;volume=11;issue=4;spage=234;epage=238;aulast=Al-Nassar;type=0