|Year : 2004 | Volume
| Issue : 1 | Page : 8-14
Comparison of caudal bupivacaine and morphine for relief of postoperative pain in children
MK Arora, S Rajeshwari, HL Kaul
Dept. of Anesthesiology and Intensive Care, AIIMS, New Delhi, India
ABSTRACT: Background and Objectives: The study was aimed to compare the efficacy, duration and side effects of combination of bupivacaine 0.25 percent with low dose morphine 0.03 mg/kg and bupivacaine 0.25 percent alone injected into the caudal space for relief of postoperative pain in children undergoing various procedures. Methods: Eighty children aged between 1-10 years undergoing urogenital, orthopedic and lower abdominal general surgical procedures were studied. In 40 patients (Group I) bupivacaine alone and in another 40 patients (Group II) morphine (0.03 mg/ kg) mixed with bupivacaine was given caudally after induction of anesthesia. Patients were selected for each of these therapies by draw of random numbers. Results: The mean duration of analgesiawas 8.2 plus-minus 2.4 hours (range 5-12 hours) in bupivacaine group and 20.8 plus-minus 3.4 hours (range 12-26 hours) in morphine mixed with bupivacaine group. No serious side effect like respiratory depression or apnea was seen in any patient and there was no significant difference in the incidence of nausea, vomiting and urinary retention between the 2 groups. Conclusions: We conclude that low dose morphine (0.03 mg/kg) combined with 0.25 percent bupivacaine given caudally gave longer duration of analgesia in children undergoing urogenital, general surgical and orthopedic procedures without significant side effects.
Dept. of Anesthesiology and Intensive Care, AIIMS, New Delhi
Source of Support: None, Conflict of Interest: None