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Journal of Indian Association of Pediatric Surgeons
     Journal of Indian Association of Pediatric Surgeons
Official journal of the Indian Association of Pediatric Surgeons         
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Year : 1999  |  Volume : 4  |  Issue : 4  |  Page : 192-195

Efficacy of OK-432 in pediatric lymphangiomas-Preliminary experience.


Department of Pediatric Surgery, All Institute of Medical Sciences, New Delhi, India

Correspondence Address:
DK Gupta
Department of Pediatric Surgery, All Institute of Medical Sciences, New Delhi
India
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Source of Support: None, Conflict of Interest: None


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ABSTRACT: Aim:Lymphangiomas are characterized by a proliferation of small lymphatics and vessels with intervening fibrous tissue and this is a common condition seen in children. Surgical excision of these leaves behind tell tale signs which could aesthetically be relevant to the child. OK-432 is a promising alternative for this condition. This study was designed to evaluate the effectiveness of OK-432 in the treatment of lymphangiomas in children. Patients and Methods:Twenty-four patients with clinical diagnosis of lymphangioma underwent the treatment, between the period 1996-1998, with OK-432 and formed the study group of this non-randomized clinical trial. Upon investigation 12 were cystic and the remaining were diffuse. Results: Seven out of the 12 cystic lymphangiomas responded very well. The remaining showed a partial response. All the 12 cases of diffuse variety showed poor response. conclusions: Intrta-lesional OK-432 is best suitable for the cystic variety of lymphangioma. this therapy has minimal side effects and should be the first choice for the treatment of cystic lymphangiomas.






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  2005 - Journal of Indian Association of Pediatric Surgeons | Published by Wolters Kluwer - Medknow 

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