|Year : 1999 | Volume
| Issue : 4 | Page : 192-195
Efficacy of OK-432 in pediatric lymphangiomas-Preliminary experience.
DK Gupta, M Bajpai, M Srinivas, A Lall, S Dave, S Ogita
Department of Pediatric Surgery, All Institute of Medical Sciences, New Delhi, India
ABSTRACT: Aim:Lymphangiomas are characterized by a proliferation of small lymphatics and vessels with intervening fibrous tissue and this is a common condition seen in children. Surgical excision of these leaves behind tell tale signs which could aesthetically be relevant to the child. OK-432 is a promising alternative for this condition. This study was designed to evaluate the effectiveness of OK-432 in the treatment of lymphangiomas in children. Patients and Methods:Twenty-four patients with clinical diagnosis of lymphangioma underwent the treatment, between the period 1996-1998, with OK-432 and formed the study group of this non-randomized clinical trial. Upon investigation 12 were cystic and the remaining were diffuse. Results: Seven out of the 12 cystic lymphangiomas responded very well. The remaining showed a partial response. All the 12 cases of diffuse variety showed poor response. conclusions: Intrta-lesional OK-432 is best suitable for the cystic variety of lymphangioma. this therapy has minimal side effects and should be the first choice for the treatment of cystic lymphangiomas.
Department of Pediatric Surgery, All Institute of Medical Sciences, New Delhi
Source of Support: None, Conflict of Interest: None
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