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Journal of Indian Association of Pediatric Surgeons
     Journal of Indian Association of Pediatric Surgeons
Official journal of the Indian Association of Pediatric Surgeons         
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Year : 1997  |  Volume : 2  |  Issue : 2  |  Page : 79-82

Pre-and pastoperative cortisol secretion in neonates undergoing surgery of esophageal atresia.


All Institute of Medical Sciences, New Delhi-110029, India

Correspondence Address:
V Bhatnagar
All Institute of Medical Sciences, New Delhi-110029
India
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Source of Support: None, Conflict of Interest: None


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ABSTRACT: Pre-and postoperative cortisol levels were measured in clotted blood of 27 neonates who underwent surgery for esophageal atresia with or without tracheo-esophageal fistula. The preoperative and 6 hours postoperative values were 40.6 plus minus 29.0 and 41.5 plus minus 33.0 meug/dl respectively (p-value not significant). These values were further analyzed with regard to various clinical and biochemical parameters. The results indicated that factors which did not significantly affect the postoperative cortisol response included age, color, temperature, weight, pneumonitis, respiratory distress, hemoglobin, blood sugar, duration of surgery, sedation, anesthetic complications, starvation and ventilatory support. The changes with regard to blood transfusion requirements were almost significant (p less than 0.06) while the amount of blood loss was directly proportional to increase in the cortisol response (p less than 0.02).






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  2005 - Journal of Indian Association of Pediatric Surgeons | Published by Wolters Kluwer - Medknow 

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